Saliency in Context (SALICON) is an ongoing effort that aims at understanding and predicting visual attention. Conventional saliency models typically rely on low-level image statistics to predict human fixations. While these models perform significantly better than chance, there is still a large gap between model prediction and human behavior. This gap is largely due to the limited capability of models in predicting eye fixations with strong semantic content, the so-called semantic gap. This paper presents a focused study to narrow the semantic gap with an architecture based on Deep Neural Network (DNN). It leverages the representational power of high-level semantics encoded in DNNs pretrained for object recognition. Two key components are fine-tuning the DNNs with an objective function based on the saliency evaluation metrics, and integrating information at different image scales. We compare our method with 14 saliency models on 6 public eye tracking benchmark datasets. Results demonstrate that our DNNs can automatically learn features for saliency prediction that surpass by a big margin the state-of-the-art. In addition, our model ranks top to date under all seven metrics on the MIT300 challenge set.